Endocrine Abstracts

Polycystic Ovary Syndrome (PCOS) is currently believed a common endocrine-plurimetabolic disorder often associated to insulin resistance, diabetes mellitus, hypertension, hyperandrogenism, dyslipidemia and obesity, pathological conditions predisposing to high cardiovascular risk. Oxidative stress and endothelial dysfunction could represent early mechanisms of the cardiovascular risk in patients with PCOS. In order to confirm this hypothesis, 25 young (23.8±1.3 yr), over-w...

Polycystic Ovary Syndrome (PCOS) is the most common endocrine disorder in women of reproductive age often associated with insulin resistance, diabetes mellitus, hyperandrogenism, dislipidemia, obesity and hypertension, pathological conditions predisposing to high cardiovascular risk. Insulin resistant subjects may have higher plasma renin activity and it is well known that aldosterone plays a well-recognized role in the pathophysiology of hypertension and in the development of...

Polycystic ovary syndrome (PCOS) is one of the most common endocrine diseases in women, affecting up to 10% of women in reproductive age. The evidence of polycystic ovaries at ultrasonography has been recently considered as a further criteria to diagnose PCOS. In order to determine whether FSH receptor gene affects hormonal and/or metabolic parameters of PCOS women the presence of FSH receptor gene mutations was investigated. Forthy women aged between 18 and 40 years with poly...